DP Receptors – Discovery of Novel BET inhibitors in a DMD mouse model

IRF1 transcriptional activity is inhibited before its degradation, recommending that HSP90 impacts IRF1 binding to DNA also

January 27, 2023

IRF1 transcriptional activity is inhibited before its degradation, recommending that HSP90 impacts IRF1 binding to DNA also. the HSP90 chaperone machine3. Cancers […]

DP Receptors

The attributing mechanisms include increased protein misfolding, coupled to impaired protein clearance by suppression of the chymotryptic activity of the 20S proteasome

November 5, 2022

by concernforhealth

The attributing mechanisms include increased protein misfolding, coupled to impaired protein clearance by suppression of the chymotryptic activity of the 20S proteasome. […]

DP Receptors

However, chemical modification analysis could not distinguish between the roles of these residues in substrate binding catalytic activity and did not provide direct evidence for his or her involvement in substrate binding

April 15, 2022

by concernforhealth

However, chemical modification analysis could not distinguish between the roles of these residues in substrate binding catalytic activity and did not provide […]

DP Receptors

[PMC free article] [PubMed] [Google Scholar]Crowell EF, Bischoff V, Desprez T, Rolland A, Stierhof Y-D, Schumacher K, Gonneau M, H?fte H, Vernhettes S

February 2, 2022

by concernforhealth

[PMC free article] [PubMed] [Google Scholar]Crowell EF, Bischoff V, Desprez T, Rolland A, Stierhof Y-D, Schumacher K, Gonneau M, H?fte H, Vernhettes […]