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Discovery of Novel BET inhibitors in a DMD mouse model

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In this test, an increased dose (50 nM) of TAE684 and an extended treatment duration of 72 hours were chosen

October 17, 2024
by concernforhealth

In this test, an increased dose (50 nM) of TAE684 and an extended treatment duration of 72 hours were chosen. dependent. Taken […]

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Shp2

Osteoporosis is the most common metabolic bone disease (2); and caused by bone density loss due to age-related changes during bone formation period as well as the internal and external factors aggravating the process

October 3, 2024
by concernforhealth

Osteoporosis is the most common metabolic bone disease (2); and caused by bone density loss due to age-related changes during bone formation […]

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Shp2

These observations support the idea that MafB imposes a particular epigenetic state in stem cells that persists in the adult B-cell compartment of Sca1-MafB mice, allowing all of us to recognize an epigenetic DNA methylation memory space of reprogrammed stem cells in the adult B cells of Sca1-MafB mice

February 13, 2023
by concernforhealth

These observations support the idea that MafB imposes a particular epigenetic state in stem cells that persists in the adult B-cell compartment […]

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Shp2

Outcomes were considered significant on the p statistically? ?0

February 9, 2023
by concernforhealth

Outcomes were considered significant on the p statistically? ?0.05 level. Results The 48 participating laboratories (see Additional file 1) returned a complete […]

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Shp2

Nasopharyngitis was regarded as due to an immune-mediated procedure, however the exact underlying pathogenetic mechanism must be clarified completely

February 8, 2023
by concernforhealth

Nasopharyngitis was regarded as due to an immune-mediated procedure, however the exact underlying pathogenetic mechanism must be clarified completely. a large healing […]

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Shp2

The OECs still in the suspension were washed twice with HBSS and trypsinized (0

November 27, 2022
by concernforhealth

The OECs still in the suspension were washed twice with HBSS and trypsinized (0.05% trypsin; PAA) until solitary cells were obtained. to […]

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Shp2

Data were collected from at least four indie experiments per time point

April 29, 2022
by concernforhealth

Data were collected from at least four indie experiments per time point. independent of the presence of MCs. We hence find no […]

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